You can use SQL Anywhere as a replicate site. If you use SQL Anywhere as a replicate site, you do not need the LTM.
The following diagram illustrates the components required for SQL Anywhere to participate in a Replication Server installation as a replicate site.
Replication Server receives data changes from primary site servers.
Replication Server connects to SQL Anywhere to apply the changes.
SQL Anywhere makes the changes to the database.
The Replication Server can use asynchronous procedure calls (APC) at replicate sites to alter data at a primary site database. If you are using APCs, the above diagram does not apply. Instead, the requirements are the same as for a primary site.