You can use Sybase Central to create or modify a destination alias.
Start Sybase Central:
Choose Start > Programs > SQL Anywhere 10 > Sybase Central.
Choose Connections > Connect to QAnywhere 10.
Specify an ODBC data source name or file, and a user ID and password if required.
Click OK.
Choose File > New > Destination Alias.
In the Alias field, type a name for the alias.
In the Destinations field, type the name of each destination on its own line.
Click OK.