In Sybase Central, you add, alter, and drop column constraints on the Constraints tab of the table or column property sheet.
Open the Tables folder.
In the right pane, double-click the table you want to alter.
On the Constraints tab, make the appropriate changes to the constraint you want to modify.
For example, to add a table or column constraint, click the Constraints tab and choose File > New > Table Check Constraint or File > New > Column Check Constraint.